Format

Send to

Choose Destination
See comment in PubMed Commons below
Front Biosci (Landmark Ed). 2009 Jun 1;14:5052-65.

Computational techniques for motif search.

Author information

1
Dept. of CSE, University of Connecticut, Storrs, CT 06269-2155, USA. rajasek@engr.uconn.edu

Abstract

In the study of protein-protein interactions, one is interested in identifying domains as well as short motifs that bind to these domains. Short motifs also confer functions to proteins such as post-translational modification, protein-protein interaction, and protein trafficking. Identification of domains is relatively easy since they are sufficiently long enough to render the likelihood of occurrences by random chance very low. On the other hand, the identification of motifs is a challenge since they are typically very short. Thus it is vital to develop efficient techniques to identify motifs. In this paper we survey some of the techniques that have been proposed in the literature for motifs identification.

PMID:
19482604
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Frontiers in Bioscience
    Loading ...
    Support Center