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J Biotechnol. 2009 Jun 1;142(1):91-5. doi: 10.1016/j.jbiotec.2009.03.022. Epub 2009 Apr 9.

A perspective: metatranscriptomics as a tool for the discovery of novel biocatalysts.

Author information

1
DOE Joint Genome Institute, Microbial Ecology Program, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA. FWarnecke@lbl.gov

Abstract

In this mini-review, advantages and current bottlenecks of metatranscriptomic-sequencing for the discovery of novel enzymes for biotechnological applications will be discussed. Comparison of this innovative approach to traditional metagenomic-sequencing will illustrate that expression profiling has a promising future as a direct and very efficient method for the discovery of novel biocatalysts, even from complex microbial communities.

PMID:
19480952
DOI:
10.1016/j.jbiotec.2009.03.022
[Indexed for MEDLINE]

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