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Science. 1991 Oct 25;254(5031):529-33.

Control of granulocytes and macrophages: molecular, cellular, and clinical aspects.

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  • 1Walter and Eliza Hall Institute of Medical Research, Post Office Royal Melbourne Hospital, Victoria, Australia.

Abstract

The production and functional activity of two important white blood cells, the granulocytes and macrophages, are regulated mainly by a group of glycoprotein colony-stimulating factors. The colony-stimulating factors have been mass-produced with recombinant technology and are now proving of value in preventing or suppressing infections in a variety of individuals with subnormal or defective formation of blood cells.

PMID:
1948028
[PubMed - indexed for MEDLINE]
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