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Science. 2009 May 29;324(5931):1190-2. doi: 10.1126/science.1171700.

Topographical and temporal diversity of the human skin microbiome.

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1
Genetics and Molecular Biology Branch, National Human Genome Research Institute, Bethesda, MD 20892, USA.

Abstract

Human skin is a large, heterogeneous organ that protects the body from pathogens while sustaining microorganisms that influence human health and disease. Our analysis of 16S ribosomal RNA gene sequences obtained from 20 distinct skin sites of healthy humans revealed that physiologically comparable sites harbor similar bacterial communities. The complexity and stability of the microbial community are dependent on the specific characteristics of the skin site. This topographical and temporal survey provides a baseline for studies that examine the role of bacterial communities in disease states and the microbial interdependencies required to maintain healthy skin.

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PMID:
19478181
PMCID:
PMC2805064
DOI:
10.1126/science.1171700
[Indexed for MEDLINE]
Free PMC Article

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