Format

Send to

Choose Destination
See comment in PubMed Commons below
Plant Cell Physiol. 2009 Jul;50(7):1232-48. doi: 10.1093/pcp/pcp075. Epub 2009 May 28.

Functional analysis of transcription factors in Arabidopsis.

Author information

1
Research Institute of Genome-Based Biofactory, National Institute of Advanced Industrial Science and Technology (AIST), Central 4, Higashi, Tsukuba, Japan.

Abstract

Transcription factors (TFs) regulate the expression of genes at the transcriptional level. Modification of TF activity dynamically alters the transcriptome, which leads to metabolic and phenotypic changes. Thus, functional analysis of TFs using 'omics-based' methodologies is one of the most important areas of the post-genome era. In this mini-review, we present an overview of Arabidopsis TFs and introduce strategies for the functional analysis of plant TFs, which include both traditional and recently developed technologies. These strategies can be assigned to five categories: bioinformatic analysis; analysis of molecular function; expression analysis; phenotype analysis; and network analysis for the description of entire transcriptional regulatory networks.

PMID:
19478073
PMCID:
PMC2709548
DOI:
10.1093/pcp/pcp075
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Silverchair Information Systems Icon for PubMed Central
    Loading ...
    Support Center