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Actas Urol Esp. 2009 Jan;33(1):90-2.

[Nested variant of urothelial carcinoma. A rare histological variant].

[Article in Spanish]

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  • 1Servicios de Urología, Hospital de Tortosa Verge de la Cinta, Tarragona.


The nested variant of urothelial carcinoma is a rare histological tumor of urinary bladder. The clinical symptoms are similar to those of the classic urothelial carcinomas. Its macroscopic appearance can be very subtle due to its preference for a submucosal growth leading to a possible delay in diagnosis. Microscopically, it is characterized by nests and tubules formation. While the neoplastic cells exhibit low-grade histological features, the growth pattern is widely infiltrative conferring this neoplasia a bad prognosis even if a radical treatment is performed. We present a case of a patient affected by a nested variant of urothelial carcinoma of urinary bladder to whom a radical cystoprostatectomy was performed and adjuvant chemotherapy was given. He is alive and free of disease one year after the diagnosis.

[PubMed - indexed for MEDLINE]
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