Format

Send to

Choose Destination
See comment in PubMed Commons below
Obstet Gynecol. 2009 Jun;113(6):1225-9. doi: 10.1097/AOG.0b013e3181a4b4b5.

The effect of fetal heart rate on the peak systolic velocity of the fetal middle cerebral artery.

Author information

1
Department of Maternal-Fetal Medicine, WakeMed Faculty Physicians, Raleigh, North Carolina 27610, USA. aswartz@wakemed.org

Abstract

OBJECTIVE:

To estimate the effect of an increase in the basal heart rate of the fetus on the middle cerebral artery peak systolic velocity (MCA-PSV).

METHODS:

This was a prospective longitudinal cohort. Patients between 14 and 36 weeks of gestation were enrolled (N=66). Ultrasound examinations were performed monthly. MCA-PSV measurements were assessed at 0-degree angle of insonation at basal fetal heart rate and after application of vibroacoustic stimulation.

RESULTS:

A total of 514 MCA-PSV measurements were obtained in 66 fetuses. No difference in fetal heart rate before and after vibroacoustic stimulation was noted before 27 weeks of gestation. A significant increase in fetal heart rate after vibroacoustic stimulation was detected from a mean+/-standard deviation gestational age of 27.1+/-1.3 weeks onward. A significant decrease in the MCA-PSV was noted between before vibroacoustic stimulation and after vibroacoustic stimulation measurements for examinations 3,4, and 5 (P<.001 for all).

CONCLUSION:

Acceleration of the fetal heart rate in the third trimester is associated with a decrease in the middle cerebral artery peak systolic velocity. Assessment of the MCA-PSV for the detection of fetal anemia, particularly in the third trimester, should be undertaken during a period of baseline fetal heart rate to avoid the potential of a false-negative result.

LEVEL OF EVIDENCE:

II.

PMID:
19461416
PMCID:
PMC3146009
DOI:
10.1097/AOG.0b013e3181a4b4b5
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Lippincott Williams & Wilkins Icon for PubMed Central
    Loading ...
    Support Center