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Gan To Kagaku Ryoho. 2009 May;36(5):721-5.

[Second-line chemotherapy for colorectal cancer].

[Article in Japanese]

Author information

1
Hokkaido University Hospital Cancer Center, Sapporo, Japan.

Abstract

For the current metastatic colorectal cancer, FOLFIRI or FOLFOX is chosen as first-line chemotherapy. Second-line irinotecan-based chemotherapy is commonly used after first-line oxaliplatin-based chemotherapy. Of course, FOLFOX becomes the second-line if FOLFIRI becomes primary therapy. It is important that these regimens combine molecular targetting agents such as Bevacizumab or Cetuximab. The addition of these new agents offers a chance to further enhance the activity of conventional chemotherapy.

PMID:
19461170
[Indexed for MEDLINE]
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