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Antimicrob Agents Chemother. 2009 Jul;53(7):3112-4. doi: 10.1128/AAC.00239-09. Epub 2009 May 18.

First report of plasmid-mediated quinolone resistance determinant qnrS1 in an Escherichia coli strain of animal origin in Italy.

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  • 1Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Viale Regina Elena 299, Rome, Italy.

Abstract

A qnrS1-positive strain of Escherichia coli was detected among 73 poultry isolates showing ciprofloxacin MICs of > or =0.125 microg/ml. The qnrS1 gene was associated with a Tn3-like transposon, as previously described to occur in a Salmonella enterica serovar Infantis strain of animal origin, but the plasmid scaffold carrying this element resembled that of a plasmid previously identified in Salmonella enterica serovar Dublin. These elements suggest genetic exchanges among Salmonella and E. coli and a potential animal reservoir for the qnr genes.

PMID:
19451298
PMCID:
PMC2704678
DOI:
10.1128/AAC.00239-09
[PubMed - indexed for MEDLINE]
Free PMC Article
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