Format

Send to

Choose Destination
Angew Chem Int Ed Engl. 2009;48(25):4605-9. doi: 10.1002/anie.200901039.

Asymmetric hydroxylative phenol dearomatization through in situ generation of iodanes from chiral iodoarenes and m-CPBA.

Author information

1
Université de Bordeaux, Institut des Sciences Moléculaires (CNRS UMR 5255), 2 rue Robert Escarpit, 33607 Pessac Cedex, France. s.quideau@iecb.u-bordeaux.fr

Abstract

'I' is all the hype: A twofold excess of iodoarene in the title reaction leads to ortho-quinols in good yields, whereas organocatalytic versions of this reaction enable subsequent epoxidation in a regio- and diastereoselective fashion. Chiral iodobiarenes led to enantioselectivities up to 50 % ee. m-CPBA = meta-chloroperoxybenzoic acid.

PMID:
19449349
DOI:
10.1002/anie.200901039

LinkOut - more resources

Full Text Sources

Other Literature Sources

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center