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Anesth Analg. 2009 Jun;108(6):1941-3. doi: 10.1213/ane.0b013e3181a286fc.

Vasoplegic syndrome during liver transplantation.

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1
Department of Anesthesia, The Southwest Hospital of The Third Military Medical University, Chongqing, 400038, China.

Abstract

A 56-yr-old woman with chronic hepatitis B and decompensated hepatic cirrhosis was treated with liver transplantation. At the beginning of the neohepatic phase, her arterial blood pressure remained at 60/40 mm Hg for approximately 40 min and did not respond to vasoconstrictive drugs. Her other clinical and laboratory values remained normal, apart from a high cardiac output and low systemic vascular resistance. This patient was diagnosed with vasoplegic syndrome and was treated with i.v. infusion of methylene blue (0.5 mg/kg) and norepinephrine. This report has potential significance to treatment in patients who undergo orthotopic liver transplantation.

PMID:
19448226
DOI:
10.1213/ane.0b013e3181a286fc
[Indexed for MEDLINE]
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