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J Virol Methods. 2009 Jul;159(1):119-21. doi: 10.1016/j.jviromet.2009.02.016. Epub 2009 Feb 24.

Assessment of sensitivity and specificity of first, second, and third generation EIA for the detection of antibodies to HIV-1 in oral fluid.

Author information

1
San Francisco Department of Public Health Laboratory, 101 Grove Street, San Francisco, CA 94102, USA.

Abstract

The performances of three blood-based immunoassays test kits were compared with regard to their ability to detect HIV-1 antibody in oral fluid. It was found that these three kits differ in their ability to detect HIV-1 antibody. Notably, a third generation EIA which has been shown to possess superior sensitivity for antibody detection in plasma appears to possess no sensitivity advantage for detecting HIV-1 antibody in oral fluid.

PMID:
19442855
DOI:
10.1016/j.jviromet.2009.02.016
[Indexed for MEDLINE]

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