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J Neurosurg Spine. 2009 Apr;10(4):329-33. doi: 10.3171/2009.1.SPINE08351.

Oncogenic osteomalacia caused by a phosphaturic mesenchymal tumor of the thoracic spine.

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1
Neurosurgery, University of Milano-Bicocca, Monza, Italy. oxosintesi@libero.it

Abstract

Phosphaturic mesenchymal tumors that cause the paraneoplastic syndrome known as oncogenic osteomalacia are rare. The authors report on the case of a 57-year-old man with a history of osteomalacia and in whom was diagnosed a thoracic spine tumor at the T-4 level. Complete tumor resection was accomplished. The histological diagnosis was phosphaturic mesenchymal tumor (mixed connective tissue variant). After lesion removal, the paraneoplastic syndrome resolved. At the 24-month follow-up, no recurrence of the disease was observed. The clinical presentation, surgical technique, and follow-up in this case were reviewed in detail.

PMID:
19441990
DOI:
10.3171/2009.1.SPINE08351
[Indexed for MEDLINE]
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