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Cephalalgia. 2010 Mar;30(3):368-72. doi: 10.1111/j.1468-2982.2009.01891.x. Epub 2010 Feb 1.

Thrombolytic treatment of ischaemic stroke occurring during a migrainous attack: a case report.

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Department of Neurology, Palacký University and University Hospital Olomouc, Stroke Centre, Czech Republic.


Authors report a case of young female suffering from the acute ischaemic stroke with right-sided hemiplegia, hemianopsia and hemihypoaesthesia during a migrainous attack without aura. Magnetic resonance imaging detected infarction in the left occipital lobe and occlusion of branches of the posterior cerebral artery (PCA). Combined treatment with systemic thrombolysis and sonothrombolysis was used, leading to the early PCA recanalization, and to a favourable clinical outcome after 1 month. Intravenous thrombolytic treatment administered within the therapeutic window may be useful in cerebral ischaemia associated with migraine when an arterial occlusion is documented.

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