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Clin Infect Dis. 2009 Jun 15;48(12):1724-8. doi: 10.1086/599225.

Nephrotoxicity associated with intravenous colistin (colistimethate sodium) treatment at a tertiary care medical center.

Author information

1
US Army, Infectious Diseases Service, Walter Reed Army Medical Center, Bldg. 2, Ward 63, 6900 Georgia Ave. NW, Washington, DC 20307, USA. joshua.hartzell@amedd.army.mil

Abstract

The incidence of acute renal failure, defined by the risk, injury, or failure criteria of the RIFLE criteria (risk, injury, failure, loss, and end-stage kidney disease), in 66 patients who received colistimethate sodium was 45%, and 21% of patients stopped therapy because of nephrotoxicity. The RIFLE criteria should be used in the future to allow for comparison of nephrotoxicity among studies.

PMID:
19438394
DOI:
10.1086/599225
[Indexed for MEDLINE]

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