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Nat Biotechnol. 2009 May;27(5):455-7. doi: 10.1038/nbt0509-455.

How to map billions of short reads onto genomes.

Author information

1
Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, USA. cole@cs.umd.edu

Abstract

Mapping the vast quantities of short sequence fragments produced by next-generation sequencing platforms is a challenge. What programs are available and how do they work?

PMID:
19430453
PMCID:
PMC2836519
DOI:
10.1038/nbt0509-455
[Indexed for MEDLINE]
Free PMC Article
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