Withdrawal of life-sustaining therapy in injured patients: variations between trauma centers and nontrauma centers

J Trauma. 2009 May;66(5):1327-35. doi: 10.1097/TA.0b013e31819ea047.

Abstract

Background: We sought to identify patient and institutional variables predictive of a withdrawal of care order (WOCO) in trauma patients. We hypothesized that the frequency of WOCO would be higher at trauma centers.

Methods: Data from the National Study on the Costs and Outcomes of Trauma were used to determine associations between WOCO status and patient characteristics, institutional characteristics, and hospital course. chi, t tests, and multivariate analysis were used to identify variables predictive of WOCO.

Results: Of 14,190 patients, 618 (4.4%) had WOCO, which accounted for 60.9% of patients who died in hospital. Age (p = <0.001), race (p = <0.001), comorbidity (p = <0.001), and injury mechanism were associated with WOCO (p = 0.03). WOCO patients had higher New Injury Severity Score (p = <0.001), lower Glasgow Coma Scale motor scores (p = <0.001), and higher incidence of midline shift on head computed tomography (p = 0.01). Trauma center status (odds ratio, 1.56; 95% confidence interval, 1.06-2.30) and closed intensive care units (odds ratio, 1.53; 95% confidence interval, 1.03-2.25) were also predictive of a WOCO. There was a sizable variation (0%-16%) in the percentage of patients with WOCO across centers.

Conclusion: Most trauma patients who die in hospital do so after a WOCO. Although trauma center status and closed intensive care units are predictive of a WOCO, variation in the percentage of patients with WOCO across all centers speaks to the complexity of these decisions. Further investigation is needed to understand how a WOCO is applied to trauma patients.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Attitude of Health Personnel
  • Chi-Square Distribution
  • Cohort Studies
  • Female
  • Hospital Mortality / trends*
  • Humans
  • Intensive Care Units / standards
  • Intensive Care Units / trends
  • Life Support Care / standards
  • Life Support Care / trends
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Outcome Assessment, Health Care
  • Predictive Value of Tests
  • Probability
  • Prospective Studies
  • Reference Values
  • Resuscitation Orders*
  • Risk Assessment
  • Trauma Centers / standards*
  • Trauma Centers / trends
  • Trauma Severity Indices
  • Withholding Treatment / standards*
  • Withholding Treatment / trends
  • Wounds and Injuries / mortality*
  • Wounds and Injuries / therapy*
  • Young Adult