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Vaccine. 2009 Mar 23;27(14):2037-41. doi: 10.1016/j.vaccine.2009.02.007. Epub 2009 Feb 12.

Australia's national Q fever vaccination program.

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National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Darlinghurst, New South Wales 2010, Australia.


A nationally funded Q fever vaccination program was introduced in Australia in 2002. The evaluation of this unique program included measures of program uptake, safety, and notification and hospitalisation rates for Q fever pre- and post-program implementation. Program uptake ranged from close to 100% amongst abattoir workers to 43% in farmers. The most commonly reported adverse event was injection site reaction. Q fever notification rates declined by over 50% between 2002 and 2006, particularly in young adult males, consistent with the profile of the abattoir workforce. Hospitalisation data showed similar trends. Available evidence suggests a significant impact of Australia's Q fever vaccination program; such a program merits consideration in other countries with a comparable Q fever disease burden.

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