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Expert Opin Investig Drugs. 2009 Jun;18(6):727-34. doi: 10.1517/13543780902810352 .

New antifungal therapies for the treatment of onychomycosis.

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Massachusetts General Hospital, 50 Staniford Street 246, Boston, MA 02114, USA.


Onychomycosis is a common disorder of nails caused by diverse spectrum of fungi ranging from dermatophytes to nondermatophyte molds and yeasts. Presently, oral and topical therapies are the mainstay of treatment with oral therapies yielding somewhat better results. Though various treatment options are available to treat onychomycosis, search for a convenient, cost effective agent with high and long-lasting cure rates is continuing. Currently, many new therapies for onychomycosis are under investigation which includes new formulations of azoles, improvement of existing topical treatments through addition of ungual enhancers and new drugs with better nail permeation.

[Indexed for MEDLINE]

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