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Lab Chip. 2009 May 21;9(10):1334-6. doi: 10.1039/b901322a. Epub 2009 Mar 18.

Optical redistribution of microparticles and cells between microwells.

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SUPA, School of Physics and Astronomy, University of St. Andrews, St. Andrews, Fife, KY16 9SS, UK.


The shaping of laser beams has developed into a powerful tool for optical micromanipulation. In this context, Airy and parabolic laser beams which follow curved trajectories have drawn considerable attention. These beams may allow clearing of microparticles through particle transport along curved paths, a concept termed "optically mediated particle clearing (OMPC)." In this communication we apply this concept to microparticles and cells within specially designed microwells. Our results open novel perspectives for the redistribution of cells between different media within a microfluidic environment.


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