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Neuropsychiatr Dis Treat. 2006 Mar;2(1):21-31.

A neuropsychiatric review of pediatric obsessive-compulsive disorder: etiology and efficacious treatments.

Author information

1
Department of Psychiatry, University of Florida, Gainesville, FL, USA. estorch@psychiatry.ufl.edu.

Abstract

Pediatric obsessive-compulsive disorder (OCD) is a chronic neuropsychiatric condition associated with broad impairments in functioning. This paper outlines current etiological theories of OCD, providing a review of neuroanatomical, neurochemical, neuroimmunological, and cognitive-behavioral explanations. Subsequently, first-line treatment modalities are discussed (serotonin reuptake inhibitors [SRIs] and cognitive-behavioral therapy [CBT] with exposure and response prevention [E/RP]) in the context of recent pharmacological, CBT, and combined trials.

KEYWORDS:

OCD; cognitive behavioral therapy; etiology; pediatric; serotonin reuptake inhibitors; treatment

PMID:
19412443
PMCID:
PMC2671737

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