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Cell Cycle. 2009 Jun 1;8(11):1681-7. Epub 2009 Jun 30.

Antioxidant defense and aging in C. elegans: is the oxidative damage theory of aging wrong?

Author information

1
Institute of Healthy Ageing and Research Department of Genetics, Evolution and Environment, University College London, London, UK. david.gems@ucl.ac.uk

Abstract

The oxidative damage theory of aging once seemed almost proven. Yet recently the buzzards have been assembling in the blue skies above it. New challenges to the theory from work using nematode worms seem set to bring them down to peck at its bones. But is the theory really dead, or does it just need to be modified?

PMID:
19411855
DOI:
10.4161/cc.8.11.8595
[Indexed for MEDLINE]
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