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J Autism Dev Disord. 2009 Jun;39(6):946-52. doi: 10.1007/s10803-009-0744-1. Epub 2009 Apr 28.

Brief report: Visual processing of faces in individuals with fragile X syndrome: an eye tracking study.

Author information

1
Department of Psychology, University of California, Davis, Davis, CA, USA. ffarzin@ucdavis.edu

Abstract

Gaze avoidance is a hallmark behavioral feature of fragile X syndrome (FXS), but little is known about whether abnormalities in the visual processing of faces, including disrupted autonomic reactivity, may underlie this behavior. Eye tracking was used to record fixations and pupil diameter while adolescents and young adults with FXS and sex- and age-matched typically developing controls passively viewed photographs of faces containing either a calm, happy, or fearful expression, preceded by a scrambled face matched on luminance. Results provide quantitative evidence for significant differences in gaze patterns and increased pupillary reactivity when individuals with FXS passively view static faces. Such abnormalities have significant implications in terms of understanding causes of gaze avoidance observed in individuals with FXS.

PMID:
19399604
PMCID:
PMC2684976
DOI:
10.1007/s10803-009-0744-1
[Indexed for MEDLINE]
Free PMC Article

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