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J Orthop Surg (Hong Kong). 2009 Apr;17(1):72-6.

Review article: Glucosamine.

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  • 1Department of Orthopaedics, Westmead Hospital, Sydney, New South Wales, Australia.


It has been claimed that glucosamine is able to alleviate pain, slow down losses of, and even restore articular cartilage in patients with damaged or osteoarthritic joints. It is classified as a food additive or nutraceutical; therefore manufacturers do not need to comply with the same regulations that apply for quality assurance within the pharmaceutical industry. Osteoarthritis can be managed by pharmacological and non-pharmacological methods. It is controversial whether glucosamine sulphate is the first structure-modifying drug commercially available. Little evidence suggests that glucosamine is superior to a placebo treatment in restoring articular cartilage.

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