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Heart. 2009 Jul;95(14):1184-91. doi: 10.1136/hrt.2008.156208. Epub 2009 Apr 26.

Strain rate evaluation of phasic atrial function in hypertension.

Author information

1
Department of Cardiology, Westmead Hospital, Westmead, 2145 NSW, Australia. suzannee@westgate.wh.usyd.edu.au

Abstract

BACKGROUND:

Strain (SI) and strain rate (SR) measure regional myocardial deformation and may be a new technique to assess phasic atrial function.

OBJECTIVE:

To examine the feasibility of using SI and SR to evaluate phasic atrial function in patients with mild hypertension (HT).

PATIENTS AND METHODS:

The study group comprised 54 patients with mild essential HT (29 women) and 80 age-matched normal controls (47 women). Standard two-dimensional and Doppler echocardiography was performed as well as Doppler tissue imaging. The following left atrial (LA) volumes were measured: (a) maximal LA volume or Vol(max); (b) minimal LA volume or Vol(min); (c) just before the "p" wave on ECG (Vol(p)). Phasic LA volumes were also calculated. Systolic (S-Sr), early diastolic (E-Sr), late diastolic (A-Sr) strain rate and SI were measured.

RESULTS:

Despite no differences in indexed maximal LA volume with only mild increases in left ventricular mass in the HT cohort compared with normal subjects (mean (SD) 86 (18) g/m(2) vs 67 (14) g/m(2); p = 0.001), E-Sr was significantly lower in the HT cohort. There was a corresponding reduction in indexed conduit volume in the HT cohort compared with normal subjects (10.5 (7.5) ml/m(2) vs 13.8 (6.1) ml/m(2); p = 0.006). Global E-Sr showed modest negative correlations with LA Vol(max) and LA ejection fraction. No significant difference was present in S-Sr, A-Sr or global atrial strain between the normal and HT cohorts.

CONCLUSION:

Mild HT results in a reduction in LA conduit volume, although maximal LA volume is unchanged. This is reflected by a reduction in E-Sr with preserved S-Sr and A-Sr.

PMID:
19398436
DOI:
10.1136/hrt.2008.156208
[Indexed for MEDLINE]

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