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Med Hypotheses. 2009 Aug;73(2):138-9. doi: 10.1016/j.mehy.2009.02.031. Epub 2009 Apr 23.

Alzheimer's disease and atherosclerosis: passers-by or brothers?

Author information

1
Department of Cardiology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, PR China.

Abstract

There seems to be little relationship between Alzheimer's disease and atherosclerotic disease for quite a long time. But current evidence from epidemiological, pathological, and clinical studies indicate an association of them both. We speculate that Alzheimer's disease and atherosclerosis are brothers but not passers-by, in molecule, especially in the light of interaction between reticulon 3(RTN3) and reticulon 4(RTN4B).

PMID:
19398282
DOI:
10.1016/j.mehy.2009.02.031
[Indexed for MEDLINE]

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