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J Comput Assist Tomogr. 1991 Nov-Dec;15(6):1059-61.

Blood-brain-barrier disruption in acute Wernicke encephalopathy: MR findings.

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Department of Neuroradiology, University Hospital, Z├╝rich, Switzerland.


The clinical and MR features of an alcoholic woman with Wernicke encephalopathy are reported. During the acute stage Gd-diethylenetriamine pentaacetic acid enhanced MR revealed damage of the blood-brain barrier bilaterally and symmetrically adjacent to the third ventricle, cerebral aqueduct, and fourth ventricle. The enhancement disappeared after successful thiamine therapy, as demonstrated in a repeat postcontrast MR 1 week later.

[Indexed for MEDLINE]

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