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Lancet Infect Dis. 2009 May;9(5):312-23. doi: 10.1016/S1473-3099(09)70083-0.

Stenotrophomonas maltophilia: an emerging opportunist human pathogen.

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Institute for Infectious Diseases, University of Bern, Bern, Switzerland.


Stenotrophomonas maltophilia has emerged as an important opportunistic pathogen in the debilitated host. S maltophilia is not an inherently virulent pathogen, but its ability to colonise respiratory-tract epithelial cells and surfaces of medical devices makes it a ready coloniser of hospitalised patients. S maltophilia can cause blood-stream infections and pneumonia with considerable morbidity in immunosuppressed patients. Management of infection is hampered by high-level intrinsic resistance to many antibiotic classes and the increasing occurrence of acquired resistance to the first-line drug co-trimoxazole. Prevention of acquisition and infection depends upon the application of modern infection-control practices, with emphasis on the control of antibiotic use and environmental reservoirs.

[Indexed for MEDLINE]

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