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J Magn Reson Imaging. 2009 May;29(5):1154-62. doi: 10.1002/jmri.21746.

Fast dixon-based multisequence and multiplanar MRI for whole-body detection of cancer metastases.

Author information

1
Department of Imaging Physics, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA. jma@di.mdacc.tmc.edu

Abstract

PURPOSE:

To develop and demonstrate the feasibility of multisequence and multiplanar MRI for whole-body cancer detection.

MATERIALS AND METHODS:

Two fast Dixon-based sequences and a diffusion-weighted sequence were used on a commercially available 1.5 T scanner for whole-body cancer detection. The study enrolled 19 breast cancer patients with known metastases and in multistations acquired whole-body axial diffusion-weighted, coronal T2-weighted, axial/sagittal pre- and postcontrast T1-weighted, as well as triphasic abdomen images. Three radiologists subjectively scored Dixon images of each series for overall image quality and fat suppression uniformity on a 4-point scale (1 = poor, 2 = fair, 3 = good, and 4 = excellent).

RESULTS:

Eighteen of the 19 patients completed the whole-body MRI successfully. The mean acquisition time and overall patient table time were 46 +/- 3 and 69 +/- 5 minutes, respectively. The average radiologists' scores for overall image quality and fat suppression uniformity were both 3.4 +/- 0.5. The image quality was consistent between patients and all completed whole-body examinations were diagnostically adequate.

CONCLUSION:

Whole-body MRI offering essentially all the most optimal tumor-imaging sequences in a typical 1-hour time slot can potentially become an appealing "one-stop-shop" for whole-body cancer imaging.

PMID:
19388121
DOI:
10.1002/jmri.21746
[Indexed for MEDLINE]

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