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Nat Rev Nephrol. 2009 May;5(5):297-300. doi: 10.1038/nrneph.2009.41.

Lead poisoning from an Ayurvedic herbal medicine in a patient with chronic kidney disease.

Author information

1
Department of Medicine, University of Toronto, Toronto, ON, Canada. suma.prakash@utoronto.ca

Abstract

BACKGROUND:

A 60-year-old man with a history of diabetes and hypertension was referred to a nephrology clinic for investigation of his elevated serum creatinine level.

INVESTIGATIONS:

Physical examination; laboratory investigations, including measurement of whole-blood lead level, body lead burden and urine albumin:creatinine ratio; history of lead exposure and use of herbal medical products; and renal ultrasonography.

DIAGNOSIS:

Stage 3 chronic kidney disease that was probably worsened by consumption of lead in the form of an Ayurvedic herbal remedy.

MANAGEMENT:

Cessation of the herbal product, followed by lead-chelation therapy with calcium disodium ethylenediaminetetraacetic acid. The patient's whole-body lead burden and blood lead level decreased to acceptable levels and his serum creatinine value was within the normal range at final follow-up.

Comment in

PMID:
19384331
DOI:
10.1038/nrneph.2009.41
[Indexed for MEDLINE]

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