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Br J Cancer. 2009 Jun 2;100(11):1697-703. doi: 10.1038/sj.bjc.6605040. Epub 2009 Apr 21.

T-regulatory cell modulation: the future of cancer immunotherapy?

Author information

1
Department of Cellular and Molecular Medicine, St George's University of London, London, UK.

Abstract

T-regulatory cells suppress anti-tumour immunity in cancer patients and in murine tumour models. Furthermore, their activity is likely to have an effect on the effectiveness of immunotherapeutic treatments for cancer. Here we describe the current status of developing clinical strategies for modulating Treg activity in cancer patients.

PMID:
19384299
PMCID:
PMC2695683
DOI:
10.1038/sj.bjc.6605040
[Indexed for MEDLINE]
Free PMC Article

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