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Photomed Laser Surg. 2009 Apr;27(2):345-9. doi: 10.1089/pho.2008.2327.

The efficacy of facial skin cancer treatment with high-energy pulsed neodymium and Nd:YAG lasers.

Author information

1
Laboratory of High Energies, The N.N. Petrov Research Institute of Oncology, St. Petersburg, Russia. oncl1@rion.spb.ru

Abstract

OBJECTIVE:

The aim of this study was to assess the curative and cosmetic efficacy of treatment for facial skin cancer using neodymium laser irradiation.

BACKGROUND DATA:

Due to the complex anatomy of the area, therapy for facial skin cancer is difficult.

MATERIALS AND METHODS:

Laser irradiation was used for the treatment of 3461 patients with 3624 facial skin cancer lesions of stages T(1-2)N(0)M(0:) 3346 basal cell skin cancers, 188 limited basal cell skin cancer recurrences, and 90 squamous cell skin cancers. Pulsed neodymium (Nd) and Nd:YAG lasers were used as the energy sources. The patients were followed-up from 3 mo to 5 y or more.

RESULTS:

Patients with basal cell skin cancer treated by irradiation with the Nd laser developed recurrences in 1.8% of cases, and patients treated with the Nd:YAG laser had a recurrence rate of 2.5%. Recurrences following treatment for basal cell skin cancer, and those of squamous cell skin cancer, after irradiation with the Nd laser appeared in 3.7% and 4.4% of patients, respectively. Overall, the frequency of facial skin cancer recurrences after treatment with laser irradiation was 2.1% of all the irradiated tumors.

CONCLUSION:

Neodymium laser irradiation is an effective method to treat facial skin cancer of stages T(1-2)N(0)M(0), and results in acceptable cosmetic results.

PMID:
19382838
DOI:
10.1089/pho.2008.2327
[Indexed for MEDLINE]

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