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Fertil Steril. 2009 Oct;92(4):1344-6. doi: 10.1016/j.fertnstert.2009.03.031. Epub 2009 Apr 14.

Sperm chromatin anomalies have an adverse effect on the outcome of conventional in vitro fertilization: a study with strictly controlled external factors.

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Department of Male Clinical Research, National Research Institute for Family Planning, Beijing, People's Republic of China.


Conflicting conclusions present in earlier studies on the relationship between sperm chromatin anomalies and outcome of conventional in vitro fertilization (IVF) may result from confounding by poorly controlled external factors. We examined the relationship of sperm chromatin parameters and outcome of conventional IVF while strictly controlling external factors.

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