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Vaccine. 2009 Mar 18;27(13):1932-7. doi: 10.1016/j.vaccine.2009.01.106. Epub 2009 Jan 31.

Economic analysis of pertussis illness in the Dutch population: implications for current and future vaccination strategies.

Author information

1
Epidemiology and Surveillance, Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands. sabine.de.greeff@rivm.nl

Abstract

To reduce pertussis disease burden new vaccination strategies are considered in many countries. Since not only health benefits, but also economical aspects play a role when introducing new vaccinations, we estimated medical costs of pertussis in the Netherlands. Besides, we retrospectively performed a cost-utility analysis of the preschool booster introduced in 2001. Our results show that annual costs for pertussis are still considerable (approximately c.1.77 million for a population of 16 million). Although infants represented only 5% of cases, they accounted for 50% of the total costs. Hence, the economic burden of pertussis is largely determined by costs per infant case (c.1490) and only to a limited degree by costs per patient in other age-groups (circa c.75). Despite a substantial reduction in the number of cases, the preschool booster was not considered cost-effective. The effectiveness of universal adolescent or adult booster strategies -- to prevent pertussis in infants -- should also be considered from an economical point of view before being implemented.

PMID:
19368774
DOI:
10.1016/j.vaccine.2009.01.106
[Indexed for MEDLINE]

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