Send to

Choose Destination
See comment in PubMed Commons below
Am J Med Sci. 2009 Apr;337(4):271-3. doi: 10.1097/MAJ.0b013e3181954187.

Sister Mary Joseph and her nodule: historical and clinical perspective.

Author information

  • 1Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.


Sister Mary Joseph's nodule is referred to a metastatic lesion of the umbilicus originating from intra-abdominal or pelvic malignant disease. Metastases from other locations have been also reported. In 1949 the English surgeon Sir Hamilton Bailey coined this term after Sister Mary Joseph (1856-1939), a superintendent nurse at St. Mary's Hospital in Rochester, Minnesota, USA, who was the first to observe the association between the umbilical nodule and intra-abdominal malignancy. In this article, we discuss both the historical and clinical perspectives of Sister Mary Joseph's nodule.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center