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Oper Dent. 2009 Mar-Apr;34(2):142-9. doi: 10.2341/08-64.

A clinical evaluation of two in-office bleaching regimens with and without tray bleaching.

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Clinical Research Section, Indiana University School of Dentistry, Department of Restorative Dentistry, Indianapolis, IN, USA.


This study evaluated the degree of color change of teeth, the rebound effect and the sensitivities of teeth and gingiva associated with the use of an in-office bleaching agent followed by an at-home bleaching agent to lighten stained teeth in an in vivo study. Thirty-seven subjects who met the Inclusion/Exclusion criteria were divided into two cells. Twenty-five subjects received three 15-minute in-office bleaching treatments in succession with 36% hydrogen peroxide (HP) on the maxillary anterior teeth, followed by at-home overnight bleaching with 15% carbamide peroxide (CP) for seven days on one side of the dental arch. Twelve other subjects received a 40-minute in-office bleaching treatment on their maxillary anterior teeth, followed by at-home overnight bleaching for seven days on one side of the dental arch with the same product. The cells of teeth on the other side of the dental arch received the same in-office treatment but were not bleached overnight for seven days. Color was subjectively evaluated using the Vitapan Classical Shade Guide and was objectively evaluated using the Chroma Meter at the baseline appointment, immediately after in-office bleaching and at 4, 7 and 14 days and 3 months after the in-office treatment. For two weeks, the subjects completed sensitivity evaluations of gingival tissues and hard tooth tissues. The cells that did not receive the at-home bleaching had significantly less color change than the cells that received at-home bleaching. The cell that was bleached for 40 minutes and received the at-home treatment had significantly less overall change (deltaE) at 14 days and 3 months than the cell that received three 15-minute treatments with the at-home treatment. Throughout the study, the subjects in the three 15-minute treatment cells had less gingival and tooth sensitivity than the other cells.

[Indexed for MEDLINE]

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