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J Rehabil Med. 2009 Apr;41(5):382-9. doi: 10.2340/16501977-0346.

Investigation of bias due to loss of participants in a Dutch multicentre prospective spinal cord injury cohort study.

Author information

1
Rehabilitation Centre Amsterdam, Overtoom 283, Institute for Fundamental and Clinical Human Movement Sciences, Faculty of Human Movement Sciences, Vrije Universiteit Amsterdam. s.de.groot@fbw.vu.nl

Abstract

OBJECTIVE:

To determine bias due to loss of participants (attrition bias) in a prospective cohort study.

DESIGN:

A multi-centre prospective cohort study.

SUBJECTS:

A total of 225 individuals with a spinal cord injury from 8 Dutch rehabilitation centres.

METHODS:

Participants were considered non-participants when no information was collected at the measurement one year after discharge from inpatient rehabilitation. Using bivariate tests participants and non-participants were compared regarding personal, lesion, function and functional characteristics determined at the beginning of inpatient rehabilitation and at discharge. A logistic regression was performed to determine which characteristics predict participation at one year after discharge.

RESULTS:

Of the participants at the start of the study, 31% (n = 69) did not perform the tests one year after discharge from inpatient rehabilitation. Variables associated with study participation one year after discharge were: higher level of education, higher well-being score at the start of rehabilitation, and a shorter length of stay in hospital and rehabilitation centre at discharge of inpatient rehabilitation.

CONCLUSION:

Selective attrition in the longitudinal study might have led to an over-estimation of some of the results of the measurement one year after discharge from inpatient rehabilitation.

PMID:
19363573
DOI:
10.2340/16501977-0346
[Indexed for MEDLINE]
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