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Biotechnol Bioeng. 2009 Aug 1;103(5):1016-22. doi: 10.1002/bit.22331.

Preparation and properties of starch acetate fibers for potential tissue engineering applications.

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Department of Textiles, Clothing & Design, 234, HECO Building, University of Nebraska-Lincoln, Lincoln, Nebraska 68583-0802, USA.


This article reports the development of fibers from starch acetates that have mechanical properties and water stability better than most polysaccharide-based biomaterials and protein fibers used in tissue engineering. In this research, starch acetates with three different degrees of substitution (DS) have been used to develop fibers for potential use as tissue engineering scaffolds. Varying the DS of starch acetate will provide fibers with different mechanical properties, hydrophilicity, and degradation behavior. Fibers made from DS 2.3 and 2.8 starch acetates have mechanical properties and water stability required for tissue engineering applications. The starch acetate fibers support the adhesion of fibroblasts demonstrating that the fibers would be suitable for tissue engineering and other medical applications.

[Indexed for MEDLINE]

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