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J Matern Fetal Neonatal Med. 2009 Apr;22(4):305-10. doi: 10.1080/14767050902801694.

The clinical significance of a positive Amnisure test in women with term labor with intact membranes.

Author information

1
Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul 110-744, Korea.

Abstract

OBJECTIVE:

The Amnisure ROM test is approved for the diagnosis of rupture of membranes (ROM). Yet, a fraction of patients with a positive test have intact membranes by sterile speculum examination. The objective of this study was to determine the clinical significance of this finding.

METHODS:

The study population consisted of four groups of nulliparous women at term: (1) not in labor without clinical evidence of ROM (n = 125); (2) in labor without clinical ROM with a negative Amnisure test (n = 56); (3) in labor without clinical ROM with a positive Amnisure test (n = 25); and (4) in labor with clinical ROM (n = 30). The Amnisure test was performed in cases without clinical ROM (Groups 1, 2 and 3).

RESULTS:

(1) The Amnisure test was positive more frequently in women in labor with intact membranes than in patients not in labor at term without ROM (30.9% (25/81 women) vs. 4.8% (6/125 women); p < 0.001); (2) patients in labor without clinical ROM with a positive Amnisure test had a significantly shorter admission-to-delivery interval than those in labor without clinical ROM with a negative Amnisure test (p < 0.05).

CONCLUSION:

(1) A positive Amnisure test is present in about one-third nulliparous women at term presenting in labor with intact membranes; (2) patients with a positive Amnisure test had a shorter admission-to-delivery interval than those with a negative test.

PMID:
19350444
PMCID:
PMC2744034
DOI:
10.1080/14767050902801694
[Indexed for MEDLINE]
Free PMC Article

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