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Res Microbiol. 2009 May;160(4):259-66. doi: 10.1016/j.resmic.2009.03.001. Epub 2009 Apr 5.

Cross-talk mechanisms in biofilm formation and responses to environmental and physiological stress in Escherichia coli.

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1
Department of Biomolecular Sciences and Biotechnology, University of Milan, Via Celoria 22, 20133 Milan, Italy. paolo.landini@unimi.it

Abstract

Switching from single-cell (planktonic) to biofilm growth (and vice versa) is regulated by a variety of environmental and physiological cues. Signals leading to activation of stress responses often lead to biofilm formation which, in turn, can trigger induction of stress response mechanisms, suggesting direct cross-talk between the two cellular processes. Regulatory mechanisms of this process include two-component regulatory systems, master regulators such as the rpoS gene and signal molecules such as cyclic-di-GMP, in a tight and complex interplay.

PMID:
19345733
DOI:
10.1016/j.resmic.2009.03.001
[Indexed for MEDLINE]
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