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Biochem Biophys Res Commun. 2009 May 22;383(1):103-7. doi: 10.1016/j.bbrc.2009.03.135. Epub 2009 Apr 1.

Fluid replacement following dehydration reduces oxidative stress during recovery.

Author information

1
Department of Physical Education, Yonsei University, Shinchon-Dong, Seodaemun-Gu, Seoul, South Korea.

Abstract

To investigate the effects of hydration status on oxidative DNA damage and exercise performance, 10 subjects ran on a treadmill until exhaustion at 80% VO(2max) during four different trials [control (C), 3% dehydration (D), 3% dehydration+water (W) or 3% dehydration+sports drink (S)]. Dehydration significantly decreased exercise time to exhaustion (D<C and S). Plasma MDA levels were significantly higher at pre-exercise in D than C. Plasma TAS was significantly lower at pre-exercise in C and S than in D, and was significantly lower in S than D at 60min of recovery. Dehydration significantly increased oxidative DNA damage during exercise, but fluid replacement with water or sports drink alleviated it equally. These results suggest that (1) dehydration impairs exercise performance and increases DNA damage during exercise to exhaustion; and (2) fluid replacement prolongs exercise endurance and attenuates DNA damage.

PMID:
19344695
DOI:
10.1016/j.bbrc.2009.03.135
[Indexed for MEDLINE]

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