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J Nat Prod. 2009 May 22;72(5):813-7. doi: 10.1021/np8006205.

Oxylipins from Dracontium loretense.

Author information

1
Dipartimento di Scienze Farmaceutiche, Università degli Studi di Salerno, Via Ponte Don Melillo, 84084 Fisciano, SA, Italy.

Abstract

Four novel oxylipins (1-4) were isolated from the n-butanol extract of the corms of Dracontium loretense. Their structures were assigned by 1D and 2D NMR analyses and electrospray ionization multistage ion trap mass spectrometry (ESI-ITMS(n)) data. Relative configurations were assigned on the basis of combined analysis of homonuclear and heteronuclear (2,3)J couplings, along with ROE data. Oxylipin 2 exhibited an immunostimulatory effect on human PBMC proliferation.

PMID:
19341262
DOI:
10.1021/np8006205
[Indexed for MEDLINE]

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