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Genes Dev. 2009 Apr 1;23(7):781-3. doi: 10.1101/gad.1787609.

An operational definition of epigenetics.

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1
Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

Abstract

A recent meeting (December 2008) regarding chromatin-based epigenetics was hosted by the Banbury Conference Center and Cold Spring Harbor Laboratory. The intent was to discuss aspects of epigenetic control of genomic function, and to arrive at a consensus definition of "epigenetics" to be considered by the broader community. It was evident that multiple mechanistic steps lead to the stable heritance of the epigenetic phenotype. Below we provide our view and interpretation of the proceedings at the meeting.

PMID:
19339683
PMCID:
PMC3959995
DOI:
10.1101/gad.1787609
[Indexed for MEDLINE]
Free PMC Article
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