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Cancer Genet Cytogenet. 1991 Sep;55(2):191-5.

A variant (2;13) translocation in rhabdomyosarcoma.

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Centre for Human Genetics, University of Leuven, Belgium.


Cytogenetic analysis of a right buttock mass from a 5-year-old boy showed translocation between an inverted chromosome 1 and a chromosome 13 as the sole cytogenetic abnormality. The breakpoint 13q14 appears to be the same as in previously reported cases of rhabdomyosarcoma (mostly of the alveolar type), but does not show involvement of 2q37. We suggest that this translocation may be a variant of the classical t(2;13)(q37;q14) found in rhabdomyosarcoma.

[Indexed for MEDLINE]

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