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Eksp Klin Farmakol. 2009 Jan-Feb;72(1):19-21.

[Antidepressant properties of afobazole in Porsolt and Nomura tests].

[Article in Russian]


Anxiolytic afobazole was shown in the experiments on outbred rats to decrease the immobility in the Porsolt and Nomura swim tests. The degree of afobazole effect in a dose of 5 mg/kg (i.p.) is similar to that of the standard antidepressant amitriptyline administered in doses of 10 mg/kg. Data obtained are testifying to the antidepressant activity of afobazole.

[Indexed for MEDLINE]

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