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Indian J Pathol Microbiol. 2009 Apr-Jun;52(2):159-63.

Quick score of hormone receptor status of breast carcinoma: correlation with the other clinicopathological prognostic parameters.

Author information

1
Department of Pathology, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka. lakminimudduwa@yahoo.com

Abstract

BACKGROUND:

Immunohistochemical assessment of the hormone receptor status of breast carcinoma is a routine investigation. However, there is no worldwide consensus on the scoring system. The Quick Score is claimed to be a reliable scoring system, which assesses both the proportion of stained cells and the intensity of staining.

AIMS:

To assess the value of Quick Score in terms of accepted clinicopathological parameters and to document the prevalence of hormone receptor-positive breast carcinomas in the study sample.

MATERIALS AND METHODS:

Clinicopathological parameters of 151 breast cancers were compared with the Quick Scores for estrogen receptor (ER) and progesterone receptor (PR) status.

RESULTS AND CONCLUSIONS:

The Quick Score for ER was 0 in 54.3% (82/151) and for PR was 0 in 51.7% (75/145), indicating no hormone receptor expression in the majority. The Nottingham grade and the mitotic count had a significant inverse relationship with the Quick Score for hormone receptor status. The Nottingham Prognostic Index (NPI) also had an inverse relationship with the hormone receptor status.

PMID:
19332901
[Indexed for MEDLINE]
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