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Epilepsy Res. 2009 Apr;84(2-3):250-3. doi: 10.1016/j.eplepsyres.2009.01.009. Epub 2009 Mar 28.

Epilepsy and multiple sclerosis: Increased risk among progressive forms.

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  • 1Epilepsy Clinic, National Institute of Neurology and Neurosurgery of Mexico, Mexico.

Abstract

Multiple sclerosis (MS) patients are at higher risk for epilepsy. Epilepsy was frequent among our MS patients (6.55%). Progressive MS forms were associated with higher incidence of epilepsy (p=0.021). Partial motor seizures were observed in five patients (62.5%) and generalized tonic-clonic in three (37.5%). Electroencephalogram (EEG) revealed epileptic activity in 62.5%. A high percentage of MS patients with epilepsy (37.5%) reported intoxication as the most severe form of adverse effect of antiepileptic therapy.

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