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Clin Vaccine Immunol. 2009 May;16(5):772-4. doi: 10.1128/CVI.00438-08. Epub 2009 Mar 25.

Good performance of immunoglobulin M assays in diagnosing genotype 3 hepatitis E virus infections.

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  • 1Laboratoire de Virologie, Institut Fédératif de Biologie, TSA 40031, CHU Toulouse Purpan, Toulouse Cedex, France.


We have evaluated three anti-hepatitis E virus (anti-HEV) immunoglobulin M (IgM) assays, the EIAgen HEV IgM assay (Adaltis), the HEV IgM enzyme-linked immunosorbent assay 3.0, and the Assure HEV IgM rapid test (MP Diagnostics), for the routine detection of acute genotype 3 HEV. Their sensitivities were fairly good (90%, 88%, and 82%), and their specificities were excellent (100%, 99.5%, and 100%).

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