Send to

Choose Destination
J Child Orthop. 2008 Dec;2(6):491-5. doi: 10.1007/s11832-008-0128-7. Epub 2008 Sep 30.

Intermittent active motion versus immobilization in the treatment of Staphylococcus aureus-induced arthritis in a rabbit model.

Author information

Laboratoire d'Antibiologie Clinique et Expérimentale UPRES EA 3826, Faculté de Médecine, Université de Nantes, Nantes, France,



This study has evaluated the effects of immobilization versus intermittent active motion on cartilage and on antibiotic efficacy in a rabbit septic arthritis model.


Rabbits were infected and assigned to one of four groups: group 1, no treatment without immobilization (allowing intermittent active motion); group 2, cast; group 3, oxacillin without immobilization; group 4, oxacillin and cast. Animals were sacrificed 21 days later. Bacterial counts and lateral radiograms were performed. A radiological score was calculated.


Immobilization had no effect on oxacillin efficacy and a deleterious effect on the radiological score.


Intermittent active motion has allowed a better cartilage healing during the treatment of septic arthritis.

Supplemental Content

Full text links

Icon for Bone and Joint Publishing Icon for PubMed Central
Loading ...
Support Center