Nano indium oxide as a recyclable catalyst for C-S cross-coupling of thiols with aryl halides under ligand free conditions

Vutukuri Prakash Reddy; Akkilagunta Vijay Kumar; Kokkirala Swapna; Kakulapati Rama Rao

doi:10.1021/ol900009a

Nano indium oxide as a recyclable catalyst for C-S cross-coupling of thiols with aryl halides under ligand free conditions

Org Lett. 2009 Apr 16;11(8):1697-700. doi: 10.1021/ol900009a.

Authors

Vutukuri Prakash Reddy¹, Akkilagunta Vijay Kumar, Kokkirala Swapna, Kakulapati Rama Rao

Affiliation

¹ Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad-500 007, India.

PMID: 19301923
DOI: 10.1021/ol900009a

Abstract

An efficient ligand-free C-S cross-coupling of aryl halides with aromatic/alkyl thiols has been developed using a catalytic amount of nanocrystalline indium oxide as a recyclable catalyst with KOH as the base in DMSO at 135 degrees C. A variety of aryl sulfides can be synthesized in excellent yields utilizing this protocol.

MeSH terms

Catalysis
Combinatorial Chemistry Techniques
Hydrocarbons, Halogenated / chemistry*
Indium / chemistry*
Ligands
Metal Nanoparticles / chemistry*
Molecular Structure
Sulfhydryl Compounds / chemistry*
Sulfides / chemical synthesis*
Sulfides / chemistry

Substances

Hydrocarbons, Halogenated
Ligands
Sulfhydryl Compounds
Sulfides
Indium
indium oxide